two-way anova analysis tool with bonferroni correction for multiple comparisons Search Results


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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA <t>with</t> <t>Bonferroni’s</t> multiple comparison tests. ( B ) Representative <t>FMT</t> (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.
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Image Search Results


Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA with Bonferroni’s multiple comparison tests. ( B ) Representative FMT (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.

Journal: Scientific Reports

Article Title: Simultaneous targeting of mitochondria and monocytes enhances neuroprotection against ischemia–reperfusion injury

doi: 10.1038/s41598-020-71326-x

Figure Lengend Snippet: Depletion of CypD did not inhibit inflammation after cerebral IR injury. ( A ) Protein level of inflammatory cytokines in homogenized cerebral tissues at 24 h after reperfusion. Data are presented as the mean ± SD (N = 4 mice per sham group, N = 8 mice per IR group). * P < 0.01 versus sham in WT mice, ** P < 0.001 versus sham in WT mice, † P < 0.05 versus sham in CypD-KO mice, †† P < 0.001 versus sham in CypD-KO mice. Statistical analyses were performed by two-way ANOVA with Bonferroni’s multiple comparison tests. ( B ) Representative FMT (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680. The graph indicates ProSense 680 concentrations in the cerebral tissues as estimated from the fluorescent intensity. The data represent the mean ± SD (N = 5–6 mice per group), and they were analyzed by one-way ANOVA followed by Bonferroni’s multiple comparison tests. FMT: fluorescence molecular tomography. FRI: fluorescence reflectance imaging.

Article Snippet: Statistical analyses were performed by two-way ANOVA with Bonferroni’s multiple comparison tests. ( B ) Representative FMT (above) and FRI (below) images demonstrating protease activities at 72 h after IR visualized by ProSense 680.

Techniques: Mouse Assay, Comparison, Fluorescence, Tomography, Imaging